(If you don't know who Dr. Seuss was and want to know click on his name above).
I find that in knowing all is impermanent I tend to savor things more and feel more prepared for those inevitable changes to come that might not be seen by my ego-mind as "enjoyable." It has helped me learn to deal with my fear of death and now I am prepared to die, whenever that present moment is born. That is because I stopped worrying about when or how it will happen and instead focused on being in the moment, being the moment and enjoying life to its fullest. So that death has just become simply another moment in the filmstrip of my karmic movie.
I tend to be a bit of a worrier and when you worry you lose out on a lot of life and before you know it you can worry your life away and miss precious opportunities to practice the Dharma in this precious life. I do my best to live life without regrets and to be happy to just be apart of this grand project we call this moment, this existence and this essence. So when my passing from this life to the next occurs I'm be able to "smile that it happened" as the sagely Dr. Seuss advises like a Zen master offering up a koan.